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If B {b1} is not empty, it too has an element with the least subscript when viewed as an element of A; call this element b2. Chromosome 21 is also the location of the genetic abnormality responsible for Down syndrome. 109 (Pt 2) 3017 [6] BlairHC,TeitelbaumSL,GhiselliRandGluckS1989Osteoclasticboneresorption by a polarized vacuolar proton pump Science 245(4920) 8557 [7] Sly W S and Hu P Y 1995 Human carbonic anhydrases and carbonic anhydrase defi- ciencies Ann.

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